Table 1.
Densitometric analysis and relative changes of all proteins analyzed
| Spot ID | Protein name | MW(Dalton) | IP(pH units) | Control
|
PTA+Vehicle
|
PTA+Sirolimus
|
|---|---|---|---|---|---|---|
| Optical density | Rel. changes vs. sham | Rel. changes vs. sham | ||||
| 104 | Lamin A | 65500 | 7.0 | 64.5±5.7 | 1.72 | 1.41 |
| 132 | Serum albumin precursor | 70900 | 6.3 | 178.5±11.9 | 0.77 | 1.08 |
| 156 | Vimentin | 53600 | 5.4 | 54.75±6.1 | 1.89 | 0.97 |
| 179 | Alpha-1-antitrypsin precursor | 46100 | 5.8 | 41.75±8.4 | 1.89 | 1.20 |
| 264 | Alpha enolase | 47400 | 7.1 | 141.00±10.4 | 1.03 | 1.11 |
| 294 | Alpha actin | 42600 | 5.5 | 187.5±9.3 | 1.30 | 0.74 |
| 307 | Alpha actin type A2 | 42500 | 6.0 | 161.75±7.8 | 1.25 | 0.92 |
| 379 | Annexin I | 39000 | 6.7 | 91.75±4.6 | 1.65 | 1.38 |
| 440 | Annexin V | 36000 | 5.2 | 71.25±3.2 | 1.69 | 1.37 |
| 194 | sequence tag | 57200 | 5.1 | 83.75±6.4 | 1.48 | 1.08 |
| 206 | sequence tag | 1754.8 | 6.4 | 56.5±4.2 | 1.47 | 1.75 |
| 510 | sequence tag | 29500 | 7.7 | 44.75±3.6 | 1.58 | 2.22 |