Table 2. Expressed mast cell chymases and chymase-like peptidases.
| Species
|
Enzyme
|
Gene
|
Features
|
|---|---|---|---|
| Human | α-Chymase | CMA1 | Stored; chymotryptic |
| Cathepsin G | CTSG | Stored; broad spectrum activity (tryptic, chymotryptic, met-ase) | |
| Mouse | α-Chymase/MCP-5 | Mcpt5 | Weakly active; elastolytic |
| β-Chymase MCP-1 | Mcpt1 | Stored; chymotryptic | |
| β-Chymase MCP-2 | Mcpt2 | Largely inactive | |
| β-Chymase MCP-4 | Mcpt4 | Stored; chymotryptic | |
| Cathepsin G | Ctsg | ? | |
| Dog | α-Chymase | CMA1 | Stored; chymotryptic |
| Cathepsin G | CTSG | ? |