Table 3.
Comparison by Spectrographic Phenotypes - Diagnostic
| Measure | e-LFCBB n=45 | e-LFCNB n=32 |
|---|---|---|
| Age (y) | 47 ± 7.3 | 53.3 ± 8.2 |
| Sex (male/female) | 36/9 | 26/6 |
| Body Mass Index (Kg/M2) | 28 ± 3 | 27.6 ± 2 |
| Epworth Sleepiness Score | 14 ± 2.8 | 14.6 ± 3.7 |
| Conventional polysomnographic analysis | ||
| Total Sleep Time (TST, min) | 232.1 ±124.3 | 171.7 ± 102.2 |
| Wake After Sleep Onset | 21.1 ± 14.6 | 22.8 ± 13.9 |
| Sleep Efficiency | 74.7 ± 16.1 | 68 ± 15.7 |
| Stage I % TST | 15.7 ± 14.9 | 21.9 ± 15.4 |
| Stage III+IV % TST | 4.4 ± 7.6 | 4.4 ± 8 |
| Stage REM %TST | 9.3 ± 7.9 | 6.3 ± 7.3 |
| Arousal index (per h of sleep) | 77.3 ± 23.1 | 89.2 ± 33.2 |
| Apnea Hypopnea Index (per h of sleep) | 37.6 ± 40.9 | 61.8 ± 40.9 |
| Central Apnea Index (per h of sleep) | 4.4 ± 6 | 6.6 ± 13.1 |
| Obstructive Apnea Index (per h of sleep) | 18.6 ± 29.5 | 36.5 ± 36 |
| Periodic Limb Movement Index (per h of sleep) | 1.8 ± 2.8 | 1.6 ± 3.8 |
| Minimal nocturnal oxygen saturation | 83 ± 7.1 | 76.8 ± 8.3 |
| Spectrographic analysis | ||
| Low Frequency Coupling (% of spectral windows) | 60.7 ± 10.1 | 64.7 ± 11.5 |
| High Frequency Coupling (% of spectral windows) | 14.3 ± 11.2 | 15.1 ± 11.2 |
| e-LFCBB (% of spectral windows) | 33 ± 8 | 32.4 ± 12.1 |
| e-LFCNB (% of spectral windows) | 0 | 12 ± 9 |
| Very low frequency coupling, % of spectral windows | 23.4 ± 5.2 | 19.9 ± 4.3 |
*Chi Square Total Sleep Time includes split night studies (40/77).
e-LFCBB: Elevated low frequency cardiopulmonary coupling – broad band
e-LFCNB: Elevated low frequency cardiopulmonary coupling – narrow band