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. Author manuscript; available in PMC: 2009 Mar 15.
Published in final edited form as: Virology. 2007 Dec 3;372(2):372–383. doi: 10.1016/j.virol.2007.10.023

Figure 3.

Figure 3

YLDV 67R and MYXV M62R can substitute C7L for its function in human and murine cell lines while CPXV 020, MYXV M63R and M64R cannot. (A). Plaque morphology of the recombinant VACV on representative cell lines. VERO, 3T3, HeLa and A431 cells were infected at a MOI of 0.01 PFU/cell with the indicated viruses. At approximately 36 hpi, GFP-expressing cells were visualized with an inverted fluorescence microscope using a 10× objective and photographed. (B). Growth curves of the recombinant VACV in HeLa cells at MOI of 5 PFU/cell. Virus yields at 0, 24 and 48 hpi were determined by plaque assay on the permissive VERO cells. The growth curves of the recombinant VACV in 3T3 and A431 were similar to the ones in HeLa cells and thus not shown.

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