Table 1.
Virus (PFU/mouse)a | Mortality | MDDb | |
Number | Percent | ||
VV-WR, UAB | |||
1.6 × 104 | 10/10 | 100 | 6.8 ± 0.8 |
1.6 × 103 | 3/10 | 30 | 8.3 ± 0.6 |
1.6 × 102 | 0/10 | 0 | --- |
16 | 0/10 | 0 | --- |
1.6 | 0/10 | 0 | --- |
VV-WR, Turner | |||
Stock 1.6 × 108 | 10/10 | 100 | 3.2 ± 0.4 |
1.6 × 107 | 10/10 | 100 | 3.9 ± 0.3 |
1.6 × 106 | 10/10 | 100 | 5.1 ± 0.3 |
1.6 × 105 | 10/10 | 100 | 6.2 ± 0.4 |
1.6 × 104 | 10/10 | 100 | 7.9 ± 1.0 |
VV Δ F2L-gfp | |||
Stock 6 × 107 | 10/10 | 100 | 4.2 ± 0.4 |
6 × 106 | 10/10 | 100 | 4.7 ± 0.5 |
6 × 105 | 10/10 | 100 | 6.1 ± 0.6 |
6 × 104 | 10/10 | 100 | 7.1 ± 0.3 |
6 × 103 | 5/10 | 50 | 8.4 ± 0.5 |
a. Anesthetized mice were inoculated intranasally with 40 μl of virus (20 μl/nostril).
b. Mean day of death (MDD) is shown with the standard deviation.