Table 5.
Risk factors for relapse during follow-up among 1039 patients with newly diagnosed second stage human African trypanosomiasis discharged alive after treatment with eflornithine
| Risk factors | Univariable | Multivariable | |||
|---|---|---|---|---|---|
| Incidence rate ratio (95% CI) | P value | Incidence rate ratio (95% CI) | P value | ||
| Male | 2.58 (1.58 to 4.23) | <0.0001 | 2.42 (1.47 to 3.97) | <0.0001 | |
| Age <15 years | 1.67 (1.06 to 2.62) | 0.027 | 1.52 (0.96 to 2.40) | 0.074 | |
| Trypanosomes in cerebrospinal fluid | 1.57 (1.02 to 2.42) | 0.040 | — | NS | |
| Cerebrospinal fluid leucocytes ×109/l: | |||||
| 21-99 v ≤20 | 2.37 (1.37 to 4.09) | 0.002 | 2.35 (1.36 to 4.06) | 0.002 | |
| ≥100 v ≤20 | 2.04 (1.19 to 3.51) | 0.010 | 1.87 (1.07 to 3.27) | 0.027 | |
| Confusion or stupor | 2.18 (1.09 to 4.35) | 0.027 | 1.74 (0.86 to 3.56) | 0.126 | |
| Oedema | 2.41 (0.59 to 9.79) | 0.219 | 3.74 (0.82 to 17.09) | 0.088 | |
| Skin diseases | 0.48 (0.15 to 1.51) | 0.209 | 0.36 (0.10 to 1.26) | 0.110 | |
NS=not significant.