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. 2007 Oct 31;81(6):1232–1250. doi: 10.1086/522238

Table 3. .

GO Characterization of the 100 Most Significantly Enriched Genes in FOXP2 High-Throughput Location Analysis[Note]

GO Level 1
and Child GO Categories
Genes
Signal transducer:
 Cell communication STC1,a KCNE1L, TIAM1,a TRAF1,a,b ATF6,a,c EPOR,a CD180,a,d CD5,a PLAUR,a,e ITPK1,b,c,e,f RALBP1, and RAB18c,f
 Synaptic transmission/synapse VAMP2, LNPEP,b,d TDO2,b RALA,a,c,d MAPK8IP1,a,e DCTN2, and MAPK7c,e
 Notch signaling pathway NCOR2,a,c SNW1,a and PSEN2a
 Wnt signaling pathway PM5, CER1,a and SFRP4
 G-protein–coupled receptor signaling CXCL2,a,d CCL19,a,d TGM2,b,c,d,e EBI2,d GNAZ,c,f PTGER1, CALCRL, and OPN1SWd
Development: HOXB6c and MAEA
 Nervous system development NEUROD2,c SPOCK1,b and PAX3c
 Organ development/morphogenesis TCF12,c LECT1, CD164,d,g SYK,a,c,e,d,g DGAT1,e PAX1,c FLT1,c,e,g TAGLN,a and SPEGc,e
Binding:
 Ion binding PYCR1,c,f RFPL3,a RCN2,a DUSP12,c,f TPO,d SOD3, and ACSL5
 Nucleic acid/nucleotide binding SNFT,a RPL22, RPL28, EIF3S10, RAD51AP1,a,d TOPBP1,a LBR,a PCCA, TUBB2B,f PEX1,f FMO4,d and SMC2a,f
 Protein binding TNNI1, SMARCB1, ALDOA, HSPB7,d PSMD1, and C13orf24
Transporter activity: SLC2A4a and ERO1L
 Ion transporter COX11,b SLC17A3,b CACNG3,b FTH1,a SLC20A1,g TRPA1, SLC25A3, SLC4A8, and SLC22A14
Catalytic activity: IFI30d and LDHAa
 Transferase FTSJ2, PIGC, FUT2, ST3GAL5, and PTK9a
 Hydrolase HYAL2, TLL2, PSMA3,a and TPP2
Cell adhesion SSX2IP,a HAS1,e SORBS3,a HAPLN1, and HRSP12f
Cellular process:
 Response to stimulus IGLL1

Note.— Genes classified as being in additional categories are indicated with the following footnotes.

a

Protein binding.

b

Ion binding.

c

Nucleic acid/nucleotide binding.

d

Response to stimulus.

e

Transferase.

f

Hydrolase.

g

Cell communication.