Table 3. .
GO Level 1 and Child GO Categories |
Genes |
Signal transducer: | |
Cell communication | STC1,a KCNE1L, TIAM1,a TRAF1,a,b ATF6,a,c EPOR,a CD180,a,d CD5,a PLAUR,a,e ITPK1,b,c,e,f RALBP1, and RAB18c,f |
Synaptic transmission/synapse | VAMP2, LNPEP,b,d TDO2,b RALA,a,c,d MAPK8IP1,a,e DCTN2, and MAPK7c,e |
Notch signaling pathway | NCOR2,a,c SNW1,a and PSEN2a |
Wnt signaling pathway | PM5, CER1,a and SFRP4 |
G-protein–coupled receptor signaling | CXCL2,a,d CCL19,a,d TGM2,b,c,d,e EBI2,d GNAZ,c,f PTGER1, CALCRL, and OPN1SWd |
Development: | HOXB6c and MAEA |
Nervous system development | NEUROD2,c SPOCK1,b and PAX3c |
Organ development/morphogenesis | TCF12,c LECT1, CD164,d,g SYK,a,c,e,d,g DGAT1,e PAX1,c FLT1,c,e,g TAGLN,a and SPEGc,e |
Binding: | |
Ion binding | PYCR1,c,f RFPL3,a RCN2,a DUSP12,c,f TPO,d SOD3, and ACSL5 |
Nucleic acid/nucleotide binding | SNFT,a RPL22, RPL28, EIF3S10, RAD51AP1,a,d TOPBP1,a LBR,a PCCA, TUBB2B,f PEX1,f FMO4,d and SMC2a,f |
Protein binding | TNNI1, SMARCB1, ALDOA, HSPB7,d PSMD1, and C13orf24 |
Transporter activity: | SLC2A4a and ERO1L |
Ion transporter | COX11,b SLC17A3,b CACNG3,b FTH1,a SLC20A1,g TRPA1, SLC25A3, SLC4A8, and SLC22A14 |
Catalytic activity: | IFI30d and LDHAa |
Transferase | FTSJ2, PIGC, FUT2, ST3GAL5, and PTK9a |
Hydrolase | HYAL2, TLL2, PSMA3,a and TPP2 |
Cell adhesion | SSX2IP,a HAS1,e SORBS3,a HAPLN1, and HRSP12f |
Cellular process: | |
Response to stimulus | IGLL1 |
Note.— Genes classified as being in additional categories are indicated with the following footnotes.
Protein binding.
Ion binding.
Nucleic acid/nucleotide binding.
Response to stimulus.
Transferase.
Hydrolase.
Cell communication.