Table 4. .
Significantly Overrepresented Co-Occurring Transcription Factor Binding Motifs
| Name (Description) and TRANSFAC Matrix |
Consensus Sequencea | P |
| AP-2 (activator protein 2): | ||
| AP2_Q6 | MKCCCSCNGGCG | <.01 |
| AP-4 (activator protein 4): | ||
| AP4_01 | WGARYCAGCTGYGGNCNK | <.01 |
| AP4_Q6 | CWCAGCTGGN | <.01 |
| ATF1 (activating transcription factor): | ||
| ATF_01 | CNSTGACGTNNNYC | <.01 |
| CAAT (CCAAT box): | ||
| CAAT_01 | NNNRRCCAATSA | <.01 |
| TFCP2 (transcription factor CP2 [also known as “LBP-1c”]): | ||
| CP2_01 | GCHCDAMCCAG | <.01 |
| CREB (cAMP-response element-binding protein): | ||
| CREB_02 | NNGNTGACGTNN | <.01 |
| CREB_Q2 | NSTGACGTAANN | <.01 |
| CREB_Q4 | NSTGACGTMANN | <.01 |
| CREBP1 (CRE-binding protein 1): | ||
| CREBP1_Q2 | VGTGACGTMACN | <.01 |
| E47: | ||
| E47_01 | VSNGCAGGTGKNCNN | <.01 |
| GATA1 (GATA-binding factor 1): | ||
| GATA1_01 | SNNGATNNNN | <.01 |
| GATA2 (GATA-binding factor 2): | ||
| GATA2_01 | NNNGATRNNN | <.01 |
| GC box (GC box elements): | ||
| GC_01 | NRGGGGCGGGGCNK | <.01 |
| Ik-2 (Ikaros 2): | ||
| IK2_01 | NNNTGGGAWNNC | <.01 |
| Lmo2 complex (complex of Lmo2 bound to Tal-1, E2A proteins, and GATA-1, half-site 1): | ||
| LMO2COM_01 | CNNCAGGTGBNN | <.05 |
| MZF1: | ||
| MZF1_01 | NGNGGGGA | <.01 |
| MZF1_02 | KNNNKAGGGGNAA | <.01 |
| NF1 (nuclear factor 1): | ||
| NF1_Q6 | NNTTGGCNNNNNNCCNNN | <.01 |
| NFY (nuclear factor Y [Y-box binding factor]): | ||
| NFY_01 | NNNRRCCAATSRGNNN | <.05 |
| NFY_C | NCTGATTGGYTASY | <.01 |
| NFY_Q6 | TRRCCAATSRN | <.01 |
| Pax-4 (Pax-4 binding sites): | ||
| PAX4_01 | NGNVGTCANGCGTGNNSNNYN | <.01 |
| PAX5 (B-cell specific activating protein): | ||
| PAX5_01 | BCNNNRNGCANBGNTGNRTAGCSGCHNB | <.01 |
| RREB-1 (Ras-responsive element binding protein 1): | ||
| RREB1_01 | CCCCAAACMMCCCC | <.01 |
| Sp1 (stimulating protein 1): | ||
| SP1_01 | GGGGCGGGGT | <.01 |
| SP1_Q6 | NGGGGGCGGGGYN | <.01 |
| USF (upstream stimulating factor): | ||
| USF_Q6_01 | GYCACGTGNC | <.01 |
a
International Union of Biochemistry ambiguity codes: R = A or G; Y = C or T; K = G or T; M = A or C; S = C or G; W = A or T; V = A, C, or G; B = C, G, or T; H = A, C, or T; D = A, G, or T; and N = A, G, C, or T.