Table 1. .

The Most-Significant Gene Sets or Pathways in the Fung et al.¹² GWA Study of PD Identified by a Modified GSEA Algorithm^[Note]

		Rank of Most Significant
Gene Set or Pathway	Set Size	SNP	Gene	Nominal P	FDR	FWER P
UDP-glycotransferase activity	89	59	41	<.001	.006	.006
O-glycan biosynthesis	23	69	49	<.001	.011	.018

Note.— Two pathways (database identifiers: GO accession number 0008194 and KEGG accession number hsa00512) demonstrate statistical significance after adjustment for multiple testing, but the SNPs and genes within these pathways cannot be detected by the most-significant SNPs/genes approach.