Table 5. .
Loci Demonstrating Significant Differential Methylation (P<.004; β>0.17) between Cerebral Cortex and Pons from the Same Individual
| Cerebral Cortex |
Pons |
||||||
| Feature IDa | Meanb | SD | Meanb | SD | Differenceb | P | False-Discovery Rate |
| HTR2A_E10_R | .62 | .06 | .84 | .04 | .22 | .002 | .05 |
| MATK_P190_R | .35 | .08 | .55 | .09 | .20 | .002 | .05 |
| WRN_P969_F | .31 | .05 | .50 | .10 | .19 | .002 | .05 |
| BCR_P346_F | .20 | .05 | .38 | .09 | .19 | .002 | .05 |
| IGF1_E394_F | .42 | .09 | .60 | .04 | .18 | .002 | .05 |
| DKFZP564O0823_P386_F | .39 | .04 | .57 | .07 | .18 | .002 | .05 |
| TNFSF10_E53_F | .54 | .13 | .20 | .05 | .34 | .004 | .05 |
| SERPINE1_P519_F | .62 | .13 | .32 | .05 | .30 | .004 | .05 |
| FGFR2_P460_R | .52 | .12 | .23 | .06 | .30 | .004 | .05 |
| AXIN1_P995_R | .53 | .16 | .82 | .06 | .29 | .004 | .05 |
| CD40_E58_R | .48 | .06 | .20 | .07 | .28 | .004 | .05 |
| SPARC_P195_F | .39 | .09 | .13 | .05 | .26 | .004 | .05 |
| PRKCDBP_P352_R | .72 | .07 | .48 | .07 | .24 | .004 | .05 |
| TJP2_P518_F | .29 | .11 | .07 | .03 | .22 | .004 | .05 |
| ZMYND10_P329_F | .19 | .08 | .39 | .11 | .21 | .004 | .05 |
| CASP10_P186_F | .72 | .06 | .52 | .06 | .20 | .004 | .05 |
| TNF_P158_F | .65 | .07 | .45 | .20 | .20 | .004 | .05 |
| CDK2_P330_R | .20 | .08 | .01 | .01 | .20 | .004 | .05 |
| FGF1_E5_F | .52 | .11 | .32 | .05 | .20 | .004 | .05 |
| CASP10_P334_F | .71 | .09 | .52 | .05 | .19 | .004 | .05 |
| MPO_P883_R | .70 | .05 | .51 | .08 | .18 | .004 | .05 |
| RAB32_P493_R | .53 | .08 | .35 | .06 | .18 | .004 | .05 |
| IL8_E118_R | .60 | .06 | .42 | .07 | .18 | .004 | .05 |
| STAT5A_E42_F | .66 | .06 | .48 | .04 | .18 | .004 | .05 |
| MMP9_P189_F | .88 | .05 | .71 | .04 | .17 | .004 | .05 |
a
Gene symbols are contained within the Feature ID before the first underscore.
b
Mean β value (fractional methylation from 0 to 1).