FIGURE 2.
NMR-derived structures of FH1-2 and FH2-3 and reconstructed FH1-3. A, backbone representations showing separate ensembles of FH1-2 (cyan) and FH2-3 (magenta) structures, each superimposed on the Cα atoms of their respective CCP 2s. B, backbone representations showing both the ensembles superposed on their mutual CCP 2s (Cα r.m.s.d. 0.78 Å). C, schematic representation of the structure of FH1-3 derived from structures of overlapping pairs and showing the boundaries of the FH1-2 and FH2-3 structures used as templates in Modeler 9v1 (55, 56). D, orthogonal view of the schematic representation in C.