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. 2008 Apr;172(4):972–979. doi: 10.2353/ajpath.2008.070159

Figure 2.

Figure 2

Anti-CD3 F(ab′)2 treatment diminished insulitis in NOD mice. A: Representative islet from untreated diabetic mice (n = 4) with infiltration of numerous lymphocytes. B: Representative islets from mice (n = 6) 10 weeks after anti-CD3 F(ab′)2 treatment. C: Representative islets from mice (n = 5) 20 weeks after anti-CD3 F(ab′)2 treatment. D: Insulitis scores of pancreatic islets from anti-CD3 F(ab′)2-treated mice (n = 8) or controls (n = 6). Seventy-two islets for control group and 94 islets for treated group were examined, respectively. Magnifications: A and C, ×200; B, ×100. Arrows denote islets.