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. Author manuscript; available in PMC: 2009 Feb 28.
Published in final edited form as: J Mol Biol. 2007 Dec 23;376(4):997–1007. doi: 10.1016/j.jmb.2007.12.030

Figure 5.

Figure 5

Effect of extensive oxidation by Cu2+ on the heat-induced protein dissociation and HDL fusion. HDL samples (2.5 mg/mL protein in buffer B) that were not oxidized (n) or oxidized to stage 7 (ox) were incubated at 95 °C for 60 min (incubation times are shown on the lines) and were analyzed by non-denaturing gel electrophoresis (A). Electron micrographs of these HDL were recorded at 25 °C before (B, C) and after 1 h incubation at 95 °C (D, E).