Figure 1.

Creation of Colon Cancer Stable Cell Lines that Express the Wild-Type or Activated PXR

A, Real-time PCR analysis on HCT116 cells stably transfected with vector, wild-type human PXR, or activated VP-PXR. B, Real-time PCR analysis on LS180 cells stably transfected with vector, or activated VP-PXR. Results are presented as averages and sd from three independent clones for each cell line. Human hepatocytes from three patients (all Caucasians, including a 45-yr-old male, a 67-yr-old female, and an 84-yr-old male) were included as a control.