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. Author manuscript; available in PMC: 2008 Mar 29.
Published in final edited form as: J Biol Chem. 2007 Aug 14;282(40):29211–29221. doi: 10.1074/jbc.M610623200

FIGURE 6. Inactivation of CaV1.2e1b/α2δ and CaV1.2e1c/α2δ currents when expressed with β1b, β2a, or β3 subunits.

FIGURE 6

A–C, original recordings of 1-s depolarizing pulses to −80, −20, −10, and 0 mV followed by 200-ms test pulses to 0 mV for each subunit combination indicated. D–F, voltage dependence of steady-state inactivation for each subunit combination. G–I, voltage dependence of inactivation constants for each combination specified. Inactivation of CaV1.2/α2δ/β1b and CaV1.2/α2δ/β3 currents were best fit with a bi-exponential function representing τfast and τslow, whereas CaV1.2/α2δ/β2a current inactivation was best fit with a single exponential. * illustrates p < 0.05.