Table 1.
Demographics, antioxidant exposure, MMSE scores, and apoE status of the study groups
Variable | Controls | MCI | AD |
---|---|---|---|
Subjects | 30 | 21 | 15 |
Age in years (SEM) | 69.20 (1.26) | 81.14 (0.73)* | 82.40 (0.70)* |
Gender M/F (%) | 13 (43.33) 17 (56.67) | 10 (42.62) 11 (52.38) | 10 (66.67) 5 (33.33) |
Education in years (SEM) | 15.03 (0.33) | 11.00 (0.27)* | 11.87 (0.48)* |
MMSE score/30 (SEM) | 29.03 (0.13) | 27.53 (0.16)* | 24.00 (0.40)*,** |
Antioxidants (%) | 3 (10.00) | 7 (33.33) | 5 (33.33) |
APOE ɛ4 allele carrier (%) | – | 5 (26.32) | 3 (27.27) |
Two tailed p-value for chi-square, Fisher’s exact and unpaired t statistics. MCI mild cognitive impairment, AD Alzheimer disease
*p < 0.0001 vs. control group
**p < 0.0001 vs. MCI group