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. Author manuscript; available in PMC: 2008 Nov 14.
Published in final edited form as: Eur J Pharmacol. 2007 Jul 13;573(1-3):60–64. doi: 10.1016/j.ejphar.2007.07.009

Table 1.

Survey of normalized IC50, Imax (% of maximal 5-HT current) and Hill slope data (±SD) of 5-HT in 5-HT3A and 5-HT3AB receptors.

DRUG RECEPTOR IC50[µM] IMAX [%] HILL COEFFICIENT
etomidate 5-HT3A 180 ± 86 96 ± 8.5 1.6 ± 0.86
  5-HT3AB 140 ± 45 101 ± 7.6 1.3 ± 0.49
propofol 5-HT3A 370 ± 151 95 ± 3.3 1.6 ± 0.66
  5-HT3AB 300 ± 125 94 ± 3.4 1.4 ± 0.51
pentobarbital 5-HT3A 520 ± 168 97 ± 2.9 1.9 ± 0.65
  5-HT3AB 270 ± 63 94 ± 3.7 1.7 ± 0.56