Fig. 2.

Effect of sodium arsenite (SA) administration on dextran sulfate sodium (DSS) colitis disease activity index. Rats were treated with 5% DSS orally, SA (10 mg/kg, intraperitoneally) followed by DSS or SA alone. Values for control rats are also indicated but overlap with those of SA. (a) Cycle 1; (b) Cycle 2; (c) Cycle 3

Disease activity index=(combined scores of weight loss (compared to Day 1 of the experiment), stool consistency and bleeding)/3; Results are expressed as the mean±SEM (n=8); ^* P<0.05, ^** P<0.01, significantly different from DSS colitis group; ^# P<0.05, compared to those of DSS at the beginning of respective cycle