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. 2008 Apr 9;3(4):e1933. doi: 10.1371/journal.pone.0001933

Table 3. A comparison of different theoretical diagnostic scenarios.

Diagnostic method Mean Delay Mean Cost Mean <1?show=[sr]?>Drop-out Rate
2 smears (Standard method)1 46.1 25.54 224.8
Same-day Diagnosis2 38.6 221.3
2 smears, treat ss-based on CXR3 38.7 21.50 218.7
2 smears, increase P(make visit)4 38.8 25.71 156.6
1-stop diagnosis5 43.4 219.8
2 smears6 43.8 24.10 219.6
3 smears7 45.2 28.00 219.6
2 smears HIV+patient cohort8 61.4 32.44 243.2
LJ culture9 66.3 183.2

Notes:

1.

Sensitivity = 0.55, 2 days delay in producing SSM test results.

2.

Sensitivity = 0.59 (same as for 3 smears), zero delay in delivering sputum, producing results and in patient collecting results.

3.

Sensitivity = 0.55, 2 days delay in producing SSM test results, P(treating ss-based on CXR) = 0.5 (up from 0.1).

4.

Sensitivity = 0.55, 2 days delay in producing SSM test results, P(make 1st visit to clinic on given day) = 0.1 (up from 0.05).

5.

Sensitivity = 0.59 (same as for 3 smears), zero delay in delivering sputum.

6.

Sensitivity = 0.59 (same as for 3 smears due to reduced work load), 2 days delay in producing SSM test results.

7.

Sensitivity = 0.59, 3 days delay in producing SSM test results.

8.

Sensitivity = 0.36, rates of abnormal CXR kept the same, culture time for ss-patients = 8 weeks (up from 6), sensitivity ss-SSM kept the same.

9.

LJ culture used in place of initial SSM test, culture time = 42 days, sensitivity = 1.0