Figure 5.
Individual Chr associated with particular traits in BXH (present study) and CXB (11) mice before and after A-subunit-Ad immunization. Chromosomal distance (megabases) is on the horizontal axes, and LRS values are on the vertical axes. GeneNetwork (GN) BXH identifiers are provided in parentheses for the following comparisons: left panels, Chr 17, TBI 2× for BXH mice (GN 10145) and CXB mice (GN 10512); Chr 3, Del T4 3× (difference between serum T4 after three immunizations and preimmunization) for BXH mice (GN 10154) and Del T4 2× (difference between serum T4 after two immunizations and preimmunization) for CXB mice (GN 10519); Chr 13, Pre-T4 (preimmunization serum T4) for BXH mice (GN 10150) and CXB mice (GN 10516); and right panels, Chr X, TBI 3× for BXH mice (GN10146) and ELISA 2× (TSHR antibodies measured by ELISA after two immunizations) for CXB mice (GN 10518); Chr 1, pre-T4 (preimmunization serum T4) for BXH mice (GN 10150) and CXB mice (GN 10516); Chr 13, pre-T4 (preimmunization serum T4), T4 3×, and Del T4 3× (difference between serum T4 after three immunizations and preimmunization) for BXH mice (GN 10150, 10152, and 10154).
