Table 4.

Energy balance in A+P:Lepr^−/− and A:Lepr^−/− mice

	Caloric intake (kcal/d)	Caloric expenditure (kcal/d)	Body mass (g)
A+P:Lepr−/−	12.22 ± 0.88	11.39 ± 0.63	42.22 ± 0.65a
No CRE	11.99 ± 0.86	11.39 ± 0.21	35.18 ± 0.60
A:Lepr−/−	14.88 ± 0.52	13.40 ± 0.22	35.21 ± 1.59b
No CRE	14.05 ± 1.05	13.23 ± 0.21	28.52 ± 0.82

Energy expenditure was measured by indirect calorimetry and based on calories expended per mouse. Caloric intake is based on cumulative chow intakes. Data are presented as means and sem. No statistically significant difference was observed in the two cohorts (n = 8 for each cohort) for caloric intake or caloric expenditure. There was a difference in body mass (P < 0.05). 

^aSignificant difference between A+P:Lepr^−/− mice and control mice. 

^bSignificant difference between A:Lepr^−/− and control mice.