Table 1.
Ventilatory Parameters in Patients with Primary Sjögren's Syndrome and Control Subjects without Primary Sjögren's Syndrome During Wake, Stage 2 Sleep, and Slow-Wave Sleep
| Wake |
Stage 2 |
SWS |
||||
|---|---|---|---|---|---|---|
| Control | SS | Control | SS | Control | SS | |
| TI, sec | 2.2 ± 0.2 | 2.0 ± 0.1 | 2.0 ± 0.1 | 2.0 ± 0.1 | 1.9 ± 0.1 | 2.0 ± 0.1 |
| TE, sec | 3.0 ± 0.3 | 2.8 ± 0.3 | 2.5 ± 0.3 | 2.7 ± 0.2 | 2.5 ± 0.2 | 2.8 ± 0.3 |
| FB, breaths/min | 12.5 ± 0.9 | 14.2 ± 1.4 | 13.8 ± 0.9 | 13.3 ± 1.0 | 14.1 ± 1.1 | 13.1 ± 1.0 |
| VTI, L | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.4 ± 0.0 | 0.4 ± 0.0* | 0.4 ± 0.0 | 0.4 ± 0.0* |
| VI, L/min | 6.8 ± 0.6 | 7.3 ± 0.7 | 5.4 ± 0.6 | 4.9 ± 0.5* | 5.1 ± 0.6 | 4.9 ± 0.7* |
| Rupper airway, cm h2o/(L/sec) | 5.3 ± 0.7 | 5.9 ± 1.1 | 20.5 ± 3.4 | 13.6 ± 3.2* | 17.2 ± 3.2 | 16.4 ± 4.3* |
| Sao2, % | 97.9 ± 0.4 | 98.2 ± 0.6 | 97.4 ± 0.5 | 97.9 ± 0.4 | 97.6 ± 0.2 | 98.0 ± 0.4 |
| ETco2, mm Hg | 41.2 ± 1.4 | 39.0 ± 1.6 | 43.6 ± 0.7 | 38.7 ± 5.1 | 45.1 ± 0.5 | 37.9 ± 6.7 |
Values are mean ± SEM. Inspiratory time, TI; expiratory time, TE; frequency of breathing, FB; inspiratory tidal volume, VTI; inspiratory minute ventilation, VI; upper airway resistance, RUA; O2 saturation, SaO2; and end-tidal CO2, ETCO2. Primary Sjögren's syndrome (SS), wake, n = 11; primary Sjögren's syndrome stage 2 sleep, n = 9; primary Sjögren's syndrome slow-wave sleep (SWS), n = 7; controls wake and stage 2 sleep, n = 8; controls SWS, n = 7. *P < 0.05 compared to wake conditions when groups were combined.