Table 2.
Comparison of Sleep Outcomes Between Diabetic Participants with and without Restless Legs Syndrome
| Outcome Variable1 | Cases (n = 18) | Controls (n = 21) | Effect Size2 | 95% CI or p value |
|---|---|---|---|---|
| Global PSQI score | 12.9 (± 3.3) | 6.7 (± 5.8) | D = 6.11d | 2.49 – 9.73 |
| Sleep category | ||||
| Good | 0 (0.0) | 8 (44.4) | (ref) | |
| Poor | 17 (100.0) | 10 (55.6) | OR = 28.3d | 1.48 – 542.99 |
| Component scores | ||||
| 1. Subjective sleep quality | 2.2 (± 0.8) | 1.0 (± 1.0) | Z = 3.22d | 0.001 |
| 2. Sleep latency | 1.9 (± 1.1) | 1.0 (± 1.2) | Z = 2.14c | 0.040 |
| 3. Sleep duration | 2.1 (± 0.9) | 1.5 (± 1.4) | Z = 1.07 | 0.308 |
| 4. Habitual sleep efficiency | 1.9 (± 1.1) | 1.1 (± 1.3) | Z = 2.22c | 0.035 |
| 5. Sleep disturbance | 1.7 (± 0.6) | 1.3 (± 0.8) | Z = 1.33 | 0.229 |
| 6. Sleep medications | 1.2 (± 1.6) | 0.2 (± 0.7) | Z = 3.91e | < 0.001 |
| 7. Daytime dysfunction | 1.6 (± 0.8) | 0.7 (± 0.9) | Z = 2.85d | 0.005 |
| ESS | 10.3 (± 5.1) | 8.4 (± 6.0) | D = 1.94 | −1.81 – 5.70 |
| FSS | 3.8 (± 1.2) | 2.6 (± 1.6) | D = 1.19c | 0.20 – 2.18 |
| CES-D | 18.4 (± 9.1) | 12.1 (± 11.6) | D = 6.25 | −0.47 – 12.96 |
| HbA1c | 7.1 (± 1.5) | 7.4 (±1.5) | D = −0.30 | −1.32 – 0.72 |
Data are reported as frequencies (%) or mean (± SD). PSQI refers to Pittsburgh Sleep Quality Index; ESS, Epworth Sleepiness Scale; FSS, Fatigue Severity Scale; CES-D, Center for Epidemiologic Studies-Depression Scale; CI, confidence interval.
aResponses within a variable may not sum to 100% due to missing values.
bCases and controls compared via a t-test, Fisher exact test, and Mann-Whitney U tests (component scores). Odds ratio (OR) for cases (with restless legs syndrome) versus controls (without restless legs syndrome), difference (D) for cases-controls, or z-values (Z) from nonparametric test.
p < 0.05;
p < 0.01;
p < 0.001