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. Author manuscript; available in PMC: 2008 Mar 31.
Published in final edited form as: J Renin Angiotensin Aldosterone Syst. 2007 Mar;8(1):23–33. doi: 10.3317/jraas.2007.003

Figure 2.

Figure 2

Quantitative in vitro autoradiographs showing AT1-receptor-mediated uptake of circulating [125I]-Ang II in the rat kidney. a: a control rat kidney; b: the kidney of a rat pretreated with losartan to block AT1-receptors before [125I]-Ang II was infused; c: renal cortical endosomal Ang II levels in the rats receiving vehicle, Ang II infusion for 2 weeks, or receiving concurrent administration of Ang II and candesartan. ** = p<0.01 vs. vehicle; # = p<0.05 vs. Ang II. Modified from References 36,40,58,102.