Table 6. ELISA antibody titer in time-point serum samples from participants in 100 and 200 µg groups.
Dose (µg) | No. participants | ELISA titres | |||
Day30 | Day 90 | Day194 | Day240 | ||
100 | 1 | 902 | 7,725 | 6,759 | 5,690 |
2 | 2,419 | 11,071 | 21,373 | 18,920 | |
3 | 5,790 | 20,964 | 41,423 | 108,568 | |
4 | 3,653 | 3,798 | 12,849 | 11,049 | |
5 | 6,502 | 3,259 | 11,157 | 10,733 | |
6 | 3,798 | 2,097 | 20,246 | 5,369 | |
7 | 2,808 | 18,167 | 26,907 | 11,869 | |
8 | 1,272 | 2,017 | 2,171 | 2,171 | |
9 | 4,025 | 4,348 | 34,269 | 7,725 | |
10 | 1,455 | 4,025 | 4,183 | 4,689 | |
Geomean | 2,740 | 5,591 | 13,070 | 9,642 | |
200 | 1 | 318 | 2,012 | 2,269 | 1,833 |
2 | 3,850 | 111,274 | 71,096 | 74,079 | |
3 | 12,864 | 37,370 | 74,079 | 37,140 | |
4 | 1,216 | 10,539 | 23,391 | 25,447 | |
5 | 667 | 3,840 | 3,619 | 2,143 | |
6 | 1,891 | 11,003 | 13,294 | 11,004 | |
7 | 1,295 | 9,908 | 12,473 | 7,074 | |
8 | 5,061 | 11,465 | 28,259 | 28,846 | |
9 | 345 | 1,023 | 1,149 | 1,764 | |
10 | 2,698 | 15,701 | 18,205 | ND | |
Geomean | 1648 | 9621 | 12579 | 12579 |
Note: A: ELISA antibody titer to the PfCP-2.9 in pre-immune serum samples(Day 0) is <1∶100
B: ELISA antibody titer to the PfCP-2.9 in sera from participants receiving the placebo injection is <1∶100
C. The first vaccination was performed on day 0 and boosted vaccination were on days of 60 and 180
D. ND: not done