Table IV.
Category of importance to human medicinea | Antimicrobial | Mean kg of active ingredient disposed per 1000 animal-daysb | 95% Confidence interval |
---|---|---|---|
I | Ampicillin-sulbactam | 0.04 × 10−3 | 0.00 × 10−3 to 1.45 × 10−3 |
Ceftiofur | 0.02 × 10−3 | 0.00 × 10−3 to 3.78 × 10−3 | |
Enrofloxacinc | 0.00 × 10−3 | 0.00 × 10−3 to 2999281383 | |
II | Aminoglycosidesd | 0.01 × 10−3 | 0.00 × 10−3 to 75.84 × 10−3 |
Macrolides | 0.54 × 10−3 | 0.21 × 10−3 to 1.39 × 10−3 | |
Penicillin | 0.59 × 10−3 | 0.24 × 10−3 to 1.46 × 10−3 | |
Trimethoprim-sulfadoxinee | 0.13 × 10−3 | 0.02 × 10−3 to 0.90 × 10−3 | |
III | Florfenicol | 0.53 × 10−3 | 0.20 × 10−3 to 1.38 × 10−3 |
Oxytetracycline | 2.37 × 10−3 | 1.51 × 10−3 to 3.73 × 10−3 | |
Spectinomycin | 0.18 × 10−3 | 0.03 × 10−3 to 0.93 × 10−3 | |
Unclassified | Tiamulinc,f | 0.01 × 10−3 | 0.00 × 10−3 to 11.04 × 10−3 |
Ranking of importance to human medicine (15).
The mean rates were significantly different between tetracycline and the following drugs: ampicillin-sulbactam, florfenicol, macrolides, penicillin, spectinomycin, and trimethoprim-sulfadoxine (pair-wise comparisons all P < 0.05). All other pair-wise comparisons of rates were not significantly different (P > 0.05).
Not labelled for cattle use at the time of the study.
Includes gentamicin and dihydrostreptomycin.
Combination products were placed in a category higher than their constituents as per CIPARS 2002 (8).
Tiamulin (a pleuromutilin) is not currently listed in Health Canada’s current categorization system.