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. 2008 Mar;72(2):109–118.

Table IV.

Rate of injectable antimicrobial use by mean kg of active ingredient/1000 animal-days (audit data) n = 21 farms

Category of importance to human medicinea Antimicrobial Mean kg of active ingredient disposed per 1000 animal-daysb 95% Confidence interval
I Ampicillin-sulbactam 0.04 × 10−3 0.00 × 10−3 to 1.45 × 10−3
Ceftiofur 0.02 × 10−3 0.00 × 10−3 to 3.78 × 10−3
Enrofloxacinc 0.00 × 10−3 0.00 × 10−3 to 2999281383
II Aminoglycosidesd 0.01 × 10−3 0.00 × 10−3 to 75.84 × 10−3
Macrolides 0.54 × 10−3 0.21 × 10−3 to 1.39 × 10−3
Penicillin 0.59 × 10−3 0.24 × 10−3 to 1.46 × 10−3
Trimethoprim-sulfadoxinee 0.13 × 10−3 0.02 × 10−3 to 0.90 × 10−3
III Florfenicol 0.53 × 10−3 0.20 × 10−3 to 1.38 × 10−3
Oxytetracycline 2.37 × 10−3 1.51 × 10−3 to 3.73 × 10−3
Spectinomycin 0.18 × 10−3 0.03 × 10−3 to 0.93 × 10−3
Unclassified Tiamulinc,f 0.01 × 10−3 0.00 × 10−3 to 11.04 × 10−3
a

Ranking of importance to human medicine (15).

b

The mean rates were significantly different between tetracycline and the following drugs: ampicillin-sulbactam, florfenicol, macrolides, penicillin, spectinomycin, and trimethoprim-sulfadoxine (pair-wise comparisons all P < 0.05). All other pair-wise comparisons of rates were not significantly different (P > 0.05).

c

Not labelled for cattle use at the time of the study.

d

Includes gentamicin and dihydrostreptomycin.

e

Combination products were placed in a category higher than their constituents as per CIPARS 2002 (8).

f

Tiamulin (a pleuromutilin) is not currently listed in Health Canada’s current categorization system.