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. 2007 Aug 30;584(Pt 3):935–949. doi: 10.1113/jphysiol.2007.142141

Table 5.

Fetal environment and growth and arginine-stimulated insulin secretion

Fetal environmental measure immediately before experiment Fetal endocrine responses to environment Fetal and placental growth



graphic file with name tjp0584-0935-mu14.jpg graphic file with name tjp0584-0935-mu15.jpg O2 content Plasma glucose Plasma insulin Plasma cortisol Fetal weight Placental weight Fetal: placental weight
122 days gestation
 Plasma AAN NS 0.424 NS NS NS −0.375 0.496 NS NS
0.031 0.069 0.043
20 17 13
 Plasma insulin NS NS NS 0.457 NS 0.691 0.673 −0.514
0.021 0.004 0.006 0.036
20 13 13 13
 Plasma insulin:AAN NS NS NS 0.440 NS 0.435 0.709 − 0.612
0.026 0.069 0.003 0.013
20 13 13 13
 AAN AUC NS −0.372 −0.349 NS −0.315 NS −0.537 −0.495 0.519
0.059 0.072 0.095 0.036 0.051 0.042
19 19 19 12 12 12
 Insulin AUC −0.302 NS NS 0.390 0.556 NS NS 0.423 NS
0.098 0.044 0.005 0.075
20 20 20 13
 Insulin secretion −0.394 NS NS 0.340 0.523 NS NS 0.431 − 0.484
0.048 0.077 0.011 0.081 0.056
19 19 19 12 12
140 days gestation
 Plasma AAN NS 0.650 0.650 NS 0.406 NS 0.570 NS NS
0.002 0.002 0.047 0.013
18 17 18 15
 Plasma insulin NS 0.650 0.650 NS 0.406 NS 0.570 NS NS
0.002 0.002 0.047 0.013
18 17 18 15
 Plasma insulin: AAN NS 0.630 0.543 0.699 NS 0.562 NS NS
0.002 0.010 < 0.001 0.012
19 18 19 16
 AAN AUC NS NS NS 0.656 NS NS 0.442 −0.351
0.002 0.049 0.100
18 15 15
 Insulin AUC NS −0.612 −0.414 −0.619 −0.617 NS −0.806 NS NS
0.003 0.049 0.003 0.003 < 0.001
18 17 18 18 15
0.396 NS NS 0.720 0.590 −0.452 NS NS NS
0.047 < 0.001 0.004 0.052
19 19 19 14
 Insulin secretion NS NS NS 0.787 0.631 NS 0.454 0.375 NS
< 0.001 0.002 0.045 0.084
18 18 15 15

Data are shown as r, p, n for each correlation.

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