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Jejunum strips from WT and IK1 KO mice, respectively, were challenged with 20 mm d-glucose or with 20 mml–phenylalanine. Tissue was previously incubated with 2 μm indomethacin to avoid cAMP-induced currents. ΔIsc values obtained with the indicated metabolite are shown. There were no differences between tissues. Data are means ±s.e.m. of 4 individual experiments each for WT and IK1 KO animals.
