Table 4.
Estimated model parameters for cerebral blood flow response to hypercapnia during control, l-NMMA, and phenylephrine infusion
Day | Gon | F1 | τon | Td | Goff | F2 | τoff |
---|---|---|---|---|---|---|---|
Control | 2.55 ± 0.71 | 56.87 ± 9.52 | 42.05 ± 22.41 | 5.94 ± 0.67 | 2.99 ± 0.92 | 52.30 ± 7.06 | 6.68 ± 1.57 |
l-NMMA | 2.37 ± 0.64 | 57.24 ± 9.06 | 34.29 ± 21.34 | 6.07 ± 2.67 | 2.56 ± 0.82† | 55.16 ± 8.10 | 6.58 ± 2.77 |
Phenylephrine | 2.50 ± 0.56 | 58.71 ± 9.12 | 15.06 ± 16.77 | 6.26 ± 1.06 | 3.03 ± 0.89 | 53.95 ± 4.38 | 6.49 ± 2.58 |
Values are means ±s.d. Abbreviations: Gon and Goff, gain terms for the on- and off-responses (cm s−1 Torr−1); F1 and F2, before and after hypercapnia (cm s−1); τon and τoff, time constant for the on- and off-responses (s); Td, time delay.
denotes a significant difference from control at P < 0.05.