Figure 2. Increased fast exocytosis at body temperature.

Representative Ca²⁺ current (I_Ca), membrane capacitance (C_m) low-pass filtered at 100 Hz, membrane conductance (G_m) and series conductance (G_s) traces (from top to bottom) elicited by depolarizations from holding potential (−87 mV) to −17 mV measured at different temperatures. The data were obtained from one IHC in which two changes in temperature were performed. Early transient changes in membrane conductance (G_m) or series conductance (G_s) were observed but these changes did not correlate temporally or in amplitude with the C_m response. For the first round of temperature changes, at room and physiological temperature, respectively: R_s= 17.9 mΩ and 11.8 mΩ; resting membrane capacitance = 9.2 pF and 9.3 pF; resting current at holding potential (−87 mV) =−31.7 pA and −82.2 pA. For the second round of temperature changes, at room and physiological temperature, respectively: R_s= 14.4 mΩ and 11.9 mΩ; resting membrane capacitance = 9.3 pF and 9.8 pF; resting current at holding potential (−87 mV) =−35.1 pA and −74.4 pA.