TABLE 2.
DONOR-DERIVED CELLS LOCALIZED IN NOD-SCID MOUSE AIRWAY AFTER SYSTEMIC ADMINISTRATION OF CORD BLOOD-DERIVED MESENCHYMAL CELLS
| Time Point | Mouse No. | Airway β2+ CK+ (% total CK+) |
|---|---|---|
| 1 d | 1 | 0.00 |
| 2 | 0.00 | |
| 3 | 0.00 | |
| Mean ± SD | 0.00 | |
| 2 wk | 1 | 0.11 |
| 2 | 0.16 | |
| 3 | 0.50 | |
| Mean ± SD | 0.25 ± 0.21 | |
| 1 mo | 1 | 0.00 |
| 2 | 0.13 | |
| 3 | 0.17 | |
| Mean ± SD | 0.1 ± 0.09 | |
| 3 mo | 1 | 0.11 |
| 2 | 0.14 | |
| 3 | 0.25 | |
| Mean ± SD | 0.17 ± 0.07 |
For definition of abbreviations, see Table 1.
β2-Microglobulin and pancytokeratin airway epithelial cells, as determined by morphology and anatomic location, were counted in five random high-power field (×40) on eight nonadjacent 5-μm sections for each lung (n = 3 for each experimental condition at each time point).