TABLE 1.
BLOOD GAS ANALYSIS FROM NEONATAL β-EPITHELIAL NA+ CHANNEL–OVEREXPRESSING MICE AND WILD-TYPE LITTERMATES*
Genotype | pH | Pco2 (mm Hg) | Po2 (mm Hg) | HCO3− (mmol/L) | BE (mmol/L) | Sat O2 (%) |
---|---|---|---|---|---|---|
Wild-type | 7.42 ± 0.01 | 48.7 ± 1.7 | 49.9 ± 2.0 | 30.8 ± 0.6 | 5.6 ± 0.5 | 83.7 ± 1.8 |
βENaC overexpressing | 7.40 ± 0.01 | 48.8 ± 1.4 | 43.1 ± 2.4† | 29.2 ± 0.6 | 3.8 ± 0.5† | 77.0 ± 2.4† |
Definition of abbreviations: BE = base excess; βENaC = β-epithelial Na+ channel; Sat O2 = O2 saturation.
n = 8–14 mice per group.
P < 0.05 compared with littermate control mice.