Figure 3.

Infection with murine gammaherpesvirus-68 (γHV68) after fluorescein isothiocyanate (FITC) impairs lung function. Mice were given an injection of FITC on Day 0 or were given saline (control). On Day 14, FITC-treated mice were given a γHV68 infection or were mock infected. Total lung capacity (A), vital capacity (B), and compliance (C) were all measured on Day 21 as described in the online supplement; n = 5 for control group and n = 10 for FITC + mock or FITC + γHV68. γHV68 infection resulted in significant impairment of lung function compared with FITC + mock in each measurement.