Figure 5.

Comparison of the [³H]muscimol and [³H]flunitrazepam binding within the PVN between rats previously subjected to neonatal maternal separation (NMS) and controls Representative autoradiographs of [³H]muscimol (A) and [³H]flunitrazepam (B) binding in PVN section for each group of rats. In these panels, the scale bar is 250 μm.C, binding curves for [³H]muscimol obtained in NMS (•) and control rats (▵) showing that NMS augments the number of GABA_A recptors within the PVN. D, binding curves for [³H]flunitrazepam obtained in NMS and control rats showing that NMS decreased the number of benzodiazepine binding sites within the PVN. For each concentration, data are expressed as means ±s.e.m.†statistically different from corresponding control value (P < 0.05).