Figure 6.

Neonatel maternal seperation (NMS) decreases GABA_A receptor α₁ subunit mRNA signal in the PVN A, comparison of representative autoradiographs showing basal GABA_A receptor α₁ subunit mRNA signal in the PVN of NMS and control rats. The scale bar is 250 μm.B, mean optical density of the α₁ subunit mRNA signal for NMS (open bars) and controls (filled bars). These data show that, within the PVN, NMS decreased α₁ subunit mRNA expression level; this subunit is the most widespread GABA binding site in the CNS. Data are expressed as means ±s.e.m.†Statistically different from corresponding control value (P < 0.05).