Table 7.

Change in Weight, Blood Pressure, Heart Rate, and Corrected QT Interval by Medication

	Mean (SD) [95% Confidence Interval]
	Baseline	Week 12
Venlafaxine
Weight, kg	68.9 (19.7) [65.7–71.9]	70.7 (20.1) [66.9–74.3]
Diastolic blood pressure, mm Hga	67.0 (8.8) [65.6–68.4]	70.3 (8.5) [68.8–71.9]
Systolic blood pressure, mm Hg	112.3 (14.0) [110.1–114.5]	115.5 (13.6) [113.0–118.0]
Heart rate, beats/minb	76.3 (11.9) [74.4–78.1]	82.3 (12.5) [80.0–84.6]
Corrected QT interval, ms	412.7 (21.4) [409.4–416.1]	410.3 (21.3) [406.3–414.3]
Selective serotonin reuptake inhibitor
Weight, kg	69.5 (19.8) [66.3–72.5]	72.4 (20.4) [68.6–76.1]
Diastolic blood pressure, mm Hg	66.3 (9.1) [64.9–67.7]	64.7 (10.2) [62.9–66.6]
Systolic blood pressure, mm Hg	111.1 (13.1) [109.0–113.1]	111.5 (13.3) [109.1–113.9]
Heart rate, beats/min	77.6 (12.4) [75.6–79.5]	77.5 (11.4) [75.4–79.6]
Corrected QT interval, ms	413.9 (18.4) [411.1–416.8]	413.5 (17.0) [410.3–416.6]

^aVenlafaxine vs selective serotonin reuptake inhibitor: t = 2.88; P = .004.

^bVenlafaxine vs selective serotonin reuptake inhibitor: t = 3.41; P = .001.