Fig. 2.

The development of sex differences in the impact of β-adrenergic activation on lung retention of MADB106 cells from prepubescence through maturity, expressed as percent of saline injected control levels of lung tumor retention in each age/sex condition (see Fig. 1). There were significant age by dose and sex by dose interactions such that at 13 weeks and older, the significant male-female difference in the magnitude of the metaproterenol (MP)-induced tumor-enhancing effect emerged. Error bars are SEM. The number above the 0.8 mg/kg MP dose bars indicates the magnitude of the MP effect compared to the sex/age matched saline injected group.