Figure 1. Comparison of chlordecone and E2 effects on serum prolactin level.
Mice were treated with 60-day sustained-release pellets containing E2 or chlordecone in the indicated amounts and euthanized 5–6 weeks later. Each point in the figure represents the results from an individual subject. Serum prolactin concentrations were significantly increased by E2 treatment, and significantly decreased by chlordecone. Results from chlordecone-treated mice showed a dose-related trend. *, p < 0.05; **, p<0.01; ***, p<0.001.