Figure 2. Comparison of chlordecone and E2 effects on prolactin receptor gene expression in B and CD4 T cells.
Mice were treated with 60-day sustained-release pellets containing E2 or chlordecone in the indicated amounts and euthanized 5–6 weeks later. Each point in the figure represents the results from an individual subject. Prolactin receptor mRNA was significantly increased in E2-treated mice in both B (Panel A) and CD4 T (Panel B) cells. Prolactin receptor mRNA in chlordecone-treated mice was not significantly different from controls.