Table 1.
Image intensity quantification on POD 5, 10 and 15 following gene transfer or UW only perfusion. Data are expressed as percentage of injected dose of 123I per gram of heart tissue (%ID/g). Image intensity was significantly higher in the Ad-NIS, Ad-NIS-CEA, Ad-NIS-CG than UW only perfused hearts on POD 5 and 10 (*p<0.05, t-test). No differences in radioiodine uptake between the groups were noted on POD 15 imaging comparing UW group with either Ad-NIS or Ad-NIS-CEA or Ad-NIS-CG group (t-test).
N | POD 5 | POD 10 | POD 15 | |
---|---|---|---|---|
UW | 3 | 0.44± 0.03 | 0.47± 0.06 | 0.45± 0.07 |
Ad-NIS | 6 | 1.1± 0.2* | 0.9± 0.07* | 0.54± 0.04 |
Ad-NIS-CEA | 6 | 1.2± 0.3* | 0.9± 0.1* | 0.57± 0.06 |
Ad-NIS-CG | 6 | 1.1± 0.1* | 0.9± 0.1* | 0.57± 0.09 |