Figure 2. Glucagon induces renal glomerular hyperfiltration in anaesthetized rats.
Intravenous glucagon infusion (50 ng · kg−1 of body weight · min−1) increased GFR by more than 30 % (A) as well as renal plasma flow (RPF) (B) over control (*P < 0.05 and **P < 0.01 compared with control). The extent of glucagon-induced hyperfiltration was similar to that induced by ANP (atrial natriuretic peptide), a well characterized renal vasodilator [32]. Data taken from [32].