Table 1.

Wild-type and mutant NKCCs, highlighting the differences in transmembrane domain 2

cDNAs and mutants	Transmembrane domain 2	Backbone	Substitution from
sNKCC1	G I G L A L L V I G T A T V V T T I T G	sNKCC1
hNKCC1	G I G L S V L V I M M A T V V T T I T G	hNKCC1
rNKCC2A	G I G L G V V I I L L S T M V T S I T G	rNKCC2A
hNCC	G I G L T W V I I L L S S F I T G I T G	hNCC
SV-MM	G I G L S V L V I M M A T V V T T I T G	sNKCC1	hNKCC1
SV-	G I G L S V L V I G T A T V V T T I T G	sNKCC1	hNKCC1
-MM	G I G L A L L V I M M A T V V T T I T G	sNKCC1	hNKCC1
GV-LL	G I G L G V L V I L L A T V V T T I T G	hNKCC1	rNKCC2A
TW-LL	G I G L T W L V I L L A T V V T T I T G	sNKCC1	hNCC