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The illustrations show two models explaining how Rad52 multimerization may facilitate nuclear localization of Rad52. Rad52 monomers are depicted as filled yellow circles. The fact that each Rad52 molecule contains a single NLS sequence is indicated by the presence of a single “NLS” in each Rad52 monomer. The nuclear pore complex is shown as blue cylinders. (A) The additive NLS model. (B) The nuclear retention model. The models are explained in detail in the text.
