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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Peptides. 2007 Nov 21;29(3):440–447. doi: 10.1016/j.peptides.2007.11.005

Table 1.

Effect of Central Infusion of MC3-R Antagonist (9.8 nmol/day)

PG-932 Saline
Insulin (ng/mL) 11.2 ± 1.4* 2.2 ± 0.3
Leptin (ng/mL) 20.2 ± 1.1* 2.7 ± 0.2
POMC (pg/100 pg Cyc) 2.5 ± 0.2 1.9 ± 0.2
AGRP (pg/100 pg Cyc) 0.8 ± 0.1* 1.6 ± 0.1
*

p < 0.0001 compared to saline controls.