Western analysis; RAW 264.7 cells were pre-treated with peptides and chemicals for 1h before stimulation with LPS, cell lysates were harvested 15 min after LPS stimulation and were subjected to Western analysis for p-p38 MAPK, which was subsequently probed with p38 MAPK antibody to measure the total content of p38 MAPK; lane a, no treatment; lane b, LPS (1μg/ml); lane c, ghrelin (100nM) + LPS (1μg/ml); lane d, SB202190 (1μg/ml) + ghrelin (100nM) + LPS (1μg/ml); lane e; D[lys-3]-GHRP-6 (1μg/ml) + ghrelin (100nM) + LPS (1μg/ml).