TABLE 1.
Parameter values, ranges, and source references
| Parameter | Definition | Estimated value | Range | References |
|---|---|---|---|---|
 |
Replicative transposition rate | 0.1 TE−1 gen−1 | — | Seleme et al. (1999); Vasilyeva et al. (1999) |
| c | Transpositional regulation parameter | 2.866 TE−1 | — | Townsend and Hartl (2000); Subramanian et al. (2007) |
 |
Element-deletion rate | 4 × 10−6 TE−1 gen−1 | — | Nuzhdin et al. (1997); Maside et al. (2000) |
 |
Initial TE fitness cost | 0.02 TE−1 | [0.01, 0.1] TE−1 | Crow and Simmons (1983); Mackay et al. (1992) |
 |
Asymptotic TE fitness cost | 10−3 TE−1 | — | Nuzhdin et al. (1997); Pasyukova et al. (2004) |
 |
Half-time of TE fitness cost decline | 5 gen | [2, 20] gen | Charlesworth (1991) |
 |
Rate of decrease in vector fitness | 1.5 | — | Charlesworth and Charlesworth (1983) |
 |
Dissociation rate | 0.05 TE−1 gen−1 | [0, 0.1] TE−1 gen−1 | Levis et al. (1985); Robertson et al. (1988) |
 |
Transpositional handicap | 0.95 | [0, 0.99] | Spradling (1986); Lampe et al. (1998) |
 |
Fitness cost of resistance gene | — | [0, 0.05] TE−1 | Beier et al. (1999); Ahmed et al. (2002) |
 |
Fitness benefit of resistance gene | — | [0, 0.05] | Appawu et al. (2003); Marrelli et al. (2007) |
| x(1,0) | Initial proportion of transgenic vectors | 0.025 | [0.01. 0.1] | Taylor et al. (2001) |