Figure 5.—

Altered benomyl sensitivity and resistance of a subset of mutant strains. Wild-type and rad9Δ/rad9Δ strains with heterozygous deletions in atg11, bfr2, elg1, mrc1, trx1, and ydr066c were grown on rich media (YPD) without or with 10 μg/ml benomyl. Although atg11Δ/ATG11, mrc1Δ/MRC1, trx1Δ/TRX1, and ydr066cΔ/YDR066C strains are sensitive to benomyl compared to wild-type strains, the heterozygous mutation confers relative resistance to benomyl in a rad9Δ/rad9Δ background. The rad9Δ/rad9Δ strain itself shows an increased sensitivity to benomyl vs. the wild-type counterpart.