TABLE 1.
Genomic positions of interparalog gene conversion tracts in the α-globin gene clusters of R. norvegicus and P. maniculatus
Genes | P-valuea | Alignment position | Length (bp) | Affected gene region |
---|---|---|---|---|
R. norvegicus | ||||
HBAT1; HBAT2 | <0.001 | 1172–2676 | 1505 | 5′-UTR: 35/35 bp |
Exon 1: 95/95 bp | ||||
Intron 1:115/115 bp | ||||
Exon 2: 205/205 bp | ||||
Intron 2: 32/185 bp | ||||
HBAT2; HBAT3 | <0.010 | 3347–3618 | 272b | 3′ flanking sequence |
P. maniculatus | ||||
HBAT1; HBAT2 | <0.001 | 1551–2540 | 990 | 5′-UTR: 35/35 bp |
Exon 1: 95/95 bp | ||||
Intron 1: 124/124 bp | ||||
Exon 2: 205/205 bp | ||||
Intron 2: 8/173 bp |
In each case the directionality of gene conversion is from the 5′ paralog to the neighboring 3′ paralog. No conversion tracts were identified in the HBA-T3 coding sequences of either species.
Calculated from the permutation test of Sawyer (1989).
The conversion tract starts 390 bp downstream of the stop codon.