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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Mech Dev. 2007 Oct 5;125(1-2):117–129. doi: 10.1016/j.mod.2007.09.013

Fig. 4. dFS inhibits DPP signaling.

Fig. 4

(A-D) Wings of adult females. (A) Wild type wing. (B) Expression of dFS with A9-GAL4 (if not lethal) results in smaller wings without patterning defects. (C) Ectopic expression of DPP with A9-GAL4 results in smaller wings due to apoptosis and vein pattern defects due to transformation of intervein into vein tissue. (D) Co-expression of dFS with DPP restores intervein tissue and the formation of veins. (E-H) brk-LacZ stainings; (I-L) SAL antibody stainings. Compared to wild type discs (E and I), increased levels of dFS results in significantly smaller discs with an expanded area of brk-LacZ staining (F) and reduced levels of SAL (J). Ubiquitous DPP expression results in over-growth, repression of brk (G), and expansion of SAL (K). In comparison to DPP alone, co-expression of dFS with DPP decreases over-growth, partially restores brk-LacZ staining (H), and reduces SAL expression to almost normal levels (L).